Bioinformatics Major (TAS)
Mission
The mission of bioinformatics undergraduate program at Ramapo College is to build a solid multidisciplinary foundation in biology, chemistry, computer science and mathematics using informatics as an interdisciplinary, cohesive tool. In advanced courses, students are trained to manage biological data, develop computational methods for analysis and interpretation of data, solve scientific problems and make new discoveries. In addition to the scientific and technical concepts, students are also exposed to the social, business, and ethical aspects of science. The bioinformatics program prepares students to obtain employment in industry and academia, pursue graduate education, careers in medicine and related disciplines, or engage in research in this technological field of great demand.
Program Goals
Bioinformatics majors should demonstrate:
- Knowledge of fundamental biological processes at organism, physiological, cellular and molecular levels.
- Basic understanding of principles of chemistry and their applications to living systems; properties of bio-molecules and their contribution to structure and function of cells.
- Understanding of computer programming methodology; including algorithm design and program development. Capability of designing and applying software tools for biological data analysis.
- Proficiency in the use of mathematical tools including discrete mathematics, calculus, and statistics.
- Integrated knowledge and technical skills gained from diverse scientific disciplines of biochemical, mathematical, computational and life sciences; understanding key problems, possible solutions, and latest advances in bioinformatics.
- Understanding of the process of scientific inquiry, preparation for rigorous research, quantitative problem solving skills, data analysis and interpretation of results.
After successfully completing the bioinformatics program, the students will be able to:
- Demonstrate knowledge of the structural and functional organization of the living cells. Describe properties of bio-molecules. Explain how macromolecules catalyze chemical transformations and build complex multi-molecular structures of the cell. Exhibit familiarity with the major techniques for studying structure and function of cells at molecular level.*
- Explain how macromolecules store and transmit hereditary information. Demonstrate understanding of their molecular structure/function relationships. Understand the impact of variation on biological function.*
- Demonstrate the ability to resolve scientific problems by applying an integrated approach derived from up-to-date technical skills of biological, chemical, mathematical and computational disciplines.*
- Demonstrate understanding of algorithms and computational methods in bioinformatics. Be able to apply existing computational tools to solve biological problems and perform data analysis.*
- Demonstrate strong programming skills. Possess an understanding of the practices and dynamics required to develop bioinformatics software.*
- Demonstrate basic understanding of the design, applications and significance of biological databases; Extract, evaluate and manipulate relevant data from large biological data sets.*
- Demonstrate the capability of making scientific observations, develop appropriate hypotheses and design experiments to test the hypotheses. Be able to statistically validate and quantitatively analyze the results obtained from the experiments, interpret the outcomes and make inferences. Write logical and cohesive scientific reports.*
- Demonstrate the capability to critically evaluate scientific literature. Design and conduct an original research project, critically analyze the results and present scientific findings orally and in a written report.*
* Check the College Catalog for the most up-to-date requirements.
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What is Bioinformatics?
Bioinformatics is a modern interdisciplinary science that uses computational techniques to help frame and resolve biological problems. Its purpose is to manage biological information and solve biological problems with the help of computer science based technology. The management involves gathering, storing, analyzing and interpreting biological data that can then be used for molecular modeling, gene discovery, assignment of functions to newly discovered genes, and studying relationships like structure and function of proteins. Bioinformatics is practiced in the fields of molecular, personalized and preventative medicine, biotechnology and nanobiotechnology. The information obtained by the application of this powerful new technology can be applied to prevent, diagnose and treat inherited and other diseases, design new drugs and vaccines, shorten the development cycle of new medicines and much more.
Why Ramapo College?
Ramapo College is one of the first primarily undergraduate colleges in the United States and the first in New Jersey to offer a baccalaureate degree in Bioinformatics. There is an great demand for Bioinformaticians to join the forefront of research areas in industry as well as academic institutions. Northern New Jersey is a hub for pharmaceutical industry and one of the largest centers of biotechnology. Ramapo College is located within a short distance from potential employers that seek work skills in Bioinformatics and offer opportunities for internships. In addition, several institutions of higher education that offer graduate degrees and research opportunities are located in and around this area. Therefore, Ramapo College is very well suited for a Bioinformatics program.
What courses are taught in the Bioinformatics major?
The curriculum for this program has been designed to lay a solid multidisciplinary foundation in modern life sciences, chemistry, mathematics, as well as cutting-edge computer technology using informatics as an interdisciplinary cohesive tool. In advanced courses, students are trained to manage biological data, develop computational methods to analyze and interpret data, solve scientific problems and make new discoveries. In addition to the scientific and technical concepts, students are also exposed to the social, business, and ethical aspects of science. Highly qualified and experienced educators teach the courses of Bioinformatics curriculum. The faculty members are actively engaged in research and typically involve undergraduate students in their projects. Students are also encouraged to present their findings at research conferences and publish their accomplishments in peer reviewed scientific journals.
What kind of laboratory facilities are there for Bioinformatics majors?
Supporting academic programs with the technology necessary for their success is top priority at Ramapo College. The College has well-maintained modern laboratories for biology, molecular biology, biochemistry, genetics, chemistry and physics that are used for the Bioinformatics program. Most of these laboratories are equipped with modern computers with Internet connections. In addition, two state of the art labs have been specially designed to teach Bioinformatics courses. The college also boasts over forty different PC and Mac based computer labs across the campus, with over 700 PCs and Macs for student use. In addition to email and web page space for students, a high end Sun System supports higher end computing needs for faculty and students. Several high-end servers are dedicated to Bioinformatics teaching and research.
How many credits are needed to graduate?
In order to graduate with a B.S. in Bioinformatics from Ramapo College, a student will have to earn a total of 128 credits. In addition to 72 credits of the core subjects, students pick 12 credits from two sets of specialized electives. Additionally, Fundamentals of Physics I and II courses are highly recommended for Bioinformatics majors. There is also provision for students to opt for Bioinformatics research that can be performed under the guidance of one of the faculty members of the program, or taken as Co-op/Internship in a suitable industry in the area.
What career options do Bioinformatics majors have?
This career-oriented program prepares the students to obtain employment in industry and academia, pursue graduate education, careers in medicine and related disciplines, or engage in research in this technological field of great demand. Potential job options for Bioinformatics graduates include: research scientist, bioinformatics programmer, project manager, database developer and administrator, technical assistant and technical sales representative (some of these may require graduate education). The Bioinformatics program also provides excellent preparation for graduate, medical & other professional programs. In addition to the pharmaceuticals, potential employers include research labs in academia, hospitals, governmental agencies, software industry and bioinformatics service industry.
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Additional Information
Research Projects
Bioinformatics students are assigned at least three separate Research Projects in succession during their junior and senior years. The projects require multidisciplinary concepts learnt in the prior courses and involve application of bioinformatics skills that the students progressively acquire during the course of the program. Students submit written reports, websites and newly designed bioinformatics software tools. [BIOL 406, BIIN 430, BIIN 450]
TAS Research Honors
Students complete a two semester sequence of independent research with a faculty member and at the end of the year present their findings in several research conferences inside as well as outside the college. Students are also required to write an in depth, journal quality paper on their project.
Journal Club
Bioinformatics majors are encouraged to join the TAS Journal Club. The goal of the club is to enhance awareness of the current research developments in specific scientific disciplines. The club meetings consist of student presentations of the pre-assigned research articles published within the last six months. The club is not only about presentations. The purpose of presentation is, in fact, to initiate scientific discussions. Open discussions are highly encouraged and anticipated.
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